2021年3月以前の成果はこちらをご覧ください。
原著論文/Original Papers
総説/Reviews
プロシーディングなど/Proceedings, etc.
原著論文/Original Papers
- Scandium Ion-Promoted Electron-Transfer Disproportionation of 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-Oxide (PTIO center dot) in an Aprotic Medium and the Regeneration Induced by Water
Yoshimi Shoji, Yuri Terashima, Kei Ohkubo,* Hiromu Ito, Kouichi Maruyama, Shunichi Fukuzumi,* and Ikuo Nakanishi*
Int. J. Mol. Sci., in preparation.
DOI:
PMID:
Released on - Title
Megumi Ueno, Minako Nyui, Ken-ichiro Matsumoto,* Ikuo Nakanishi, Hiroko P. Indo,* Akira Fujii, Masanobu Nagano, Jitbanjong Tangpong, Hideyuki J. Majima*
Journal Title, in contribution.
DOI:
PMID:
Released on - Title
Kei Ohkubo, Ikuo Nakanishi, Ken-ichi Yamada,* et al.
Redox Biol., under revision.
DOI:
PMID:
Released on - Reactive Oxygen Species Induced by Indomethacin Enhance Accumulation of Heme Carrier Protein 1 and Hematoporphyrin Accumulation In Vitro and In Vivo in a Brain Tumor Model
Hidehiro Kohzuki, Hiromu Ito, Hiromi Kurokawa, Hirofumi Matsui,* Tetsuya Yamamoto, and Eiichi Ishikawa
J. Clin. Biochem. Nutr., in press. Open access
DOI: 10.3164/jcbn.23-20
PMID:
Released on February 1, 2024 - Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress—Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol?
Daisuke Masuda, Ikuo Nakanishi,* Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsui-Chuan Yen, Daret K. St Clair, Hiroko P. Indo,* and Hideyuki J. Majima*
Biomolecules, 14 (1), 128 (2024). Open access
DOI: 10.3390/biom14010128
PMID: 38275757
Released on January 19, 2024 - Hair Follicle Damage after 100 mGy Low-Dose Fractionated X-ray Irradiation and the Protective Effects of TEMPOL, a Stable Nitroxide Radical, against Radiation
Yoshihiro Kawabata, Tomoko Fukushige, Hiroko P. Indo, Ken-ichiro Matsumoto,* Megumi Ueno, Ikuo Nakanishi, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Sirirat Surinkaew, Jitbanjong Tangpong, Takuro Kanekura, and Hideyuki J. Majima*
Radiat. Res., 201 (2), 115-125 (2024).
DOI: 10.1667/RADE-23-00167.1
PMID: 38211765
Released on January 12, 2024 - Enhanced Inhibition of Cancer Cell Migration by a Planar Catechin Analog
Hiromu Ito,* Yoshimi Shoji, Ken-ichiro Matsumoto, Kiyoshi Fukuhara,* and Ikuo Nakanishi*
ACS Med. Chem. Lett., 15 (2), 310-313 (2024).
DOI: 10.1021/acsmedchemlett.3c00499
PMID: 38352823
Released on January 10, 2024 - Photodynamic Therapy for X-ray-Induced Radiation-Resistant Cancer Cells
Hiromu Ito,* Yoshimi Shoji, Megumi Ueno, Ken-ichiro Matsumoto, and Ikuo Nakanishi*
Pharmaceutics, 15 (11), 2536 (2023). Open access
DOI: 10.3390/pharmaceutics15112536
PMID: 38004516
Released on October 26, 2023 - Enhancement of Cytotoxic Effects with ALA-PDT on Treatment of Radioresistant Cancer Cells
Takafumi Ikeda, Hiromi Kurokawa,* Hiromu Ito,* Kiichiro Tsuchiya, and Hirofumi Matsui*
J. Clin. Biochem. Nutr., 74 (1), 17-21 (2024). Open access
DOI: 10.3164/jcbn.23-79
PMID: 38292126
Released on October 3, 2023 - Anti-Cancer Effect of a Planar Catechin Analog through the Decrease in Mitochondrial Membrane Potential
Hiromu Ito,* Yoshimi Shoji, Ken-ichiro Matsumoto, Kiyoshi Fukuhara,* and Ikuo Nakanishi*
ACS Med. Chem. Lett., 14 (10), 1478-1481 (2023).
DOI: 10.1021/acsmedchemlett.3c00328
PMID: 37849552
Released on October 3, 2023 - Water-Induced Regeneration of a 2,2-Diphenyl-1-picrylhydrazyl Radical after Its Scandium Ion-Promoted Electron-Transfer Disproportionation in an Aprotic Medium
Ikuo Nakanishi,* Yoshimi Shoji, Kei Ohkubo,* Hiromu Ito, and Shunichi Fukuzumi*
Molecules, 28 (13), 5002 (2023). Open access
DOI: 10.3390/molecules28135002
PMID: 37446663
Released on June 26, 2023 - In Vitro Radical-Scavenging Mechanism of Melatonin and Its In Vivo Protective Effect against Radiation-Induced Lipid Peroxidation
Kailash Manda,* Kei Ohkubo,* Yoshimi Shoji, A. K. M. Raushan Kabir Zoardar, Masato Kamibayashi, Toshihiko Ozawa, Kazunori Anzai, and Ikuo Nakanishi*
Redox Biochem. Chem., 3-4, 100003 (2023). Open access
DOI: 10.1016/j.rbc.2023.100003
Released on April 11, 2023 - Effects of X-ray Irradiation on the Redox Status of Mouse Colorectal Tissues
Megumi Ueno, Raj Kumar Parajuri, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto,* Ikuo Nakanishi, Ichio Aoki, and Akira Sumiyoshi
Adv. Redox Res., 8, 100067 (2023). Open access
DOI: 10.1016/j.arres.2023.100067
Released on March 26, 2023 - Evidence of Nrf2/Keap1 Signaling Regulation by Mitochondria-Generated Reactive Oxygen Species in RGK1 Cells
Hiroko P. Indo,* Daisuke Masuda, Sompong Srburee, Hiromu Ito, Ikuo Nakanishi, Ken-ichiro Matsumoto, Samlee Mankhetkorn, Moragot Chatatikun, Sirirat Surinkaew, Lunla Udomwech, Fumitaka Kawami, Takafumi Ichikawa, Hirofumi Matsui, Jitbanjong Tangpong, and Hideyuki J. Majima*
Biomolecules, 13 (3), 445 (2023). Open access
DOI: 10.3390/biom13030445
PMID: 36979380
Released on February 27, 2023 - DTPA-Bound Planar Catechin with Potent Antioxidant Activity Triggered by Fe3+ Coordination
Kiyoshi Fukuhara,* Ikuo Nakanishi, Kohei Imai, Mirei Mizuno, Ken-ichiro Matsumoto, and Akiko Ohno
Antioxidants, 12 (2), 225 (2023). Open access
DOI: 10.3390/antiox12020225
PMID: 36829782
Released on January 18, 2023 - Effects of Selenium Deficiency on Biological Results of X-ray and Carbon-Ion Beam Irradiation in Mice
Megumi Ueno, Sayaka Shibata, Ikuo Nakanishi, Ichio Aoki, Ken-ichi Yamada, and Ken-ichiro Matsumoto*
J. Clin. Biochem. Nutr., 72 (2), 107-116 (2023). Open access
DOI: 10.3164/jcbn.22-57
PMID: 36936873
Released on December 8, 2022 - Acetic Acid Enhances the Effect of Photodynamic Therapy in Gastric Cancer Cells via the Production of Reactive Oxygen Species
Hiromi Kurokawa, Hiromu Ito, Daisuke Matano, Masahiko Terasaki, and Hirofumi Matsui*
J. Clin. Biochem. Nutr., 71 (3) 206-211 (2022). Open access
DOI: 10.3164/jcbn.22-34
PMID: 36447491
Released on August 4, 2022 - Importance of Locations of Iron Ions to Elicit Cytotoxicity Induced by a Fenton-Type Reaction
Kintaro Igarashi, Yoshimi Shoji, Emiko Sekine-Suzuki, Megumi Ueno, Ken-ichiro Matsumoto,* Ikuo Nakanishi, and Koji Fukui
Cancers, 14 (15), 3642 (2022). Open access
DOI: 10.3390/cancers14153642
PMID: 35892902
Released on July 27, 2022 - Effect of Magnesium Ion on the Radical-Scavenging Rate of Pterostilbene in an Aprotic Medium: Mechanistic Insight into the Antioxidative Reaction of Pterostilbene
Ikuo Nakanishi,* Yoshimi Shoji, Kei Ohkubo,* Megumi Ueno, Kei Shimoda, Ken-ichiro Matsumoto, Kiyoshi Fukuhara,* and Hiroki Hamada*
Antioxidants, 11 (2), 340 (2022). Open access
DOI: 10.3390/antiox11020340
PMID: 35204222
Released on February 9, 2022 - Estimation of the Local Concentration of the Markedly Dense Hydroxyl Radical Generation Induced by X-rays in Water
Ken-ichiro Matsumoto,* Megumi Ueno, Yoshimi Shoji, and Ikuo Nakanishi
Molecules, 27 (3), 592 (2022). Open access
DOI: 10.3390/molecules27030592
PMID: 35163857
Released on January 18, 2022 - Simplifying Quantitative Measurement of Free Radical Species Using an X-Band EPR Spectrometer
Yusuke Makino, Megumi Ueno, Yoshimi Shoji, Minako Nyui, Ikuo Nakanishi, Koji Fukui, and Ken-ichiro Matsumoto*
J. Clin. Biochem. Nutr., 70 (3), 213-221 (2022). Open access
DOI: 10.3164/jcbn.21-83
PMID: 35692674
Released on December 25, 2021 - Electrochemical Redox Behavior of 2,2-Diphenyl-1-picrylhydrazyl Radical Solubilized by beta-Cyclodextrin in Water
Ikuo Nakanishi* and Yoshimi Shoji
Electrochem. Commun., 134, 107190 (2022). Open access
DOI: 10.1016/j.elecom.2021.107190
Released on December 24, 2021 - Tunneling in the Hydrogen-Transfer Reaction from a Vitamin E Analog to an Inclusion Complex of 2,2-Diphenyl-1-picrylhydrazyl Radical with beta-Cyclodextrin in an Aqueous Buffer Solution at Ambient Temperature
Ikuo Nakanishi,* Yoshimi Shoji, Kei Ohkubo,* and Shunichi Fukuzumi*
Antioxidants, 10 (12), 1966 (2021). Open access
DOI: 10.3390/antiox10121966
PMID: 34943069
Released on December 8, 2021 - Effects of Loading a Magnetic Field Longitudinal to the LInear Particle-Beam Track on Yields of Reactive Oxygen Species in Water
Ken-ichiro Matsumoto,* Ikuo Nakanishi, Yasushi Abe, Shinji Sato, Ryosuke Kohno, Dousatsu Sakata, Kota Mizushima, Sung Hyun Lee, and Taku Inaniwa
Free Radical Res., 55 (5), 547-555 (2021). Open access
DOI: 10.1080/10715762.2021.1970151
PMID: 34569399
Released on September 27, 2021 - Effects of LET on Oxygen-Dependent and -Independent Generation of Hydrogen Peroxide in Water Irradiated by Carbon-Ion Beams
Ken-ichiro Matsumoto,* Megumi Ueno, Minako Nyui, Yoshimi Shoji, and Ikuo Nakanishi
Free Radical Res., 55 (6), 589-594 (2021). Open access
DOI: 10.1080/10715762.2021.1915489
PMID: 34519601
Released on September 14, 2021 - Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Imaging
Ken-ichiro Matsumoto,* Ikuo Nakanishi, Zhivko Zhelev, Rumiana Bakalova, and Ichio Aoki
Antioxid. Redox Signaling, 36 (1-3), 95-121 (2022). Open access
DOI: 10.1089/ars.2021.0110
PMID: 34148403
Released on June 19, 2021 - Protective Effects of Amino Acids on Plasmid DNA Damage Induced by Therapeutic Carbon Ions
Katsunori Yogo,* Chieko Murayama, Ryoichi Hirayama, Ken-ichiro Matsumoto, Ikuo Nakanishi, Hiromichi Ishiyama, and Hiroshi Yasuda
Radiat. Res., 196 (2), 197-203 (2021).
DOI: 10.1667/RADE-21-00033.1
PMID: 34043797
Released on May 27, 2021
総説/Reviews
- On 'Spin Trapping of Superoxide and Hydroxyl Radical: Practical Aspect' by Eli Finkelstein, Gerald M. Rosen and Elmer J. Rauckman
Toshihiko Ozawa* and Ikuo Nakanishi
Arch. Biochem. Biophys., 726, 109191 (2022).
DOI: 10.1016/j.abb.2022.109191
PMID: 35318035
Released on March 19, 2022
プロシーディングなど/Proceedings, etc.
- Analysis of a Planar Catechin Analog on Cancer Cellular Inhibition
Hiromu Ito, Yoshimi Shoji, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, and Ikuo Nakanishi
Free Radical Biol. Med., 208 (Supplement 1), S124-S125 (2023).
DOI: 10.1016/j.freeradbiomed.2023.10.283
Released on November 1, 2023 - pH Effect on the Kinetic Isotope Effect in the Hydrogen Transfer from Trolox to Water-Solubilized 2,2-Diphenyl-1-picrylhydrazyl Radical in Phosphate Buffer Solutions
Ikuo Nakanishi, Yoshimi Shoji, and Kei Ohkubo
Free Radical Biol. Med., 192 (Supplement 1), 131 (2022).
DOI: 10.1016/j.freeradbiomed.2022.10.243
Released on November 1, 2022 - Evaluation of Redox Responses of Mouse Colorectum Tissue after X-ray Irradiation
Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki, and Akira Sumiyoshi
Free Radical Biol. Med., 192 (Supplement 1), 128-129 (2022).
DOI: 10.1016/j.freeradbiomed.2022.10.238
Released on November 1, 2022 - Adjunctive Effects with Continual X-ray Irradiation for Effective Photodynamic Therapy
Hiromu Ito and Ikuo Nakanishi
Free Radical Biol. Med., 192 (Supplement 1), 125 (2022).
DOI: 10.1016/j.freeradbiomed.2022.10.231
Released on November 1, 2022 - pH Effect on the Scavenging Reaction of Ascorbic Acid against Selected Radicals in Phosphate Buffer Solutions
Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Toshihiko Ozawa, Ken-ichiro Matsumoto, and Shunichi Fukuzumi
Free Radical Biol. Med., 180 (Supplement 1), S64 (2022).
DOI: 10.1016/j.freeradbiomed.2021.12.146
Released on February 20, 2022 - Initial Molecular Geometry of Radiation-Induced Reactive Species in Water
Ken-ichiro Matsumoto, Megumi Ueno, Yoshimi Shoji, and Ikuo Nakanishi
Free Radical Biol. Med., 180 (Supplement 1), S63-S64 (2022).
DOI: 10.1016/j.freeradbiomed.2021.12.145
Released on February 20, 2022